mRNA half-lives and culture generation times

Range Table - link
Organism Bacteria Escherichia coli
Reference Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A. 2002 Jul 23 99(15):9697-702. p.9699 table 1PubMed ID12119387
Method Researchers report the results of investigations of the individual half-lives and relative abundance of the 4,288 predicted and documented mRNAs encoded by the E. coli genome by using two-color DNA microarrays.
Comments Approximately 80% of half-lives ranged between 3 and 8 min in M9 + glucose medium, and 99% of the half-lives measured were between 1 and 18 min. In LB, 99% of half-lives in LB were between 1 and 15 min.
Entered by Uri M
ID 106836