| Range |
Table - link
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Bernstein JA, Lin PH, Cohen SN, Lin-Chao S. Global analysis of Escherichia coli RNA degradosome function using DNA microarrays. Proc Natl Acad Sci U S A. 2004 Mar 2 101(9):2758-63PubMed ID14981237
|
| Method |
To investigate the degradosome's proposed role as an RNA decay machine, researchers used DNA microarrays to globally assess alterations in the steady-state abundance and decay of 4,289 E. coli mRNAs at single-gene resolution in bacteria carrying mutations in the degradosome constituents RNase E, polynucleotide phosphorylase, RhlB helicase, and enolase. |
| Comments |
Median mRNA half-lives were determined for each functional class (as annotated in Riley, ref. 1) in strains K10, N3433, SH3208 and MG1655. Categories were then ranked from 1 to 16, from lowest to highest stability in each strain. |
| Entered by |
Uri M |
| ID |
104323 |