Diffusion coefficient of rRNA in nucleus
| Range | 0.03-0.1 µm^2/sec |
|---|---|
| Organism | Mammalian tissue culture cell |
| Reference | Misteli T. Physiological importance of RNA and protein mobility in the cell nucleus. Histochem Cell Biol. 2008 Jan129(1):5-11PubMed ID17994245 |
| Comments | RNA motion within the nucleus is rapid and non-directional. Several methodological approaches involving fluorescently labeled, microinjected, engineered or endogenous RNAs demonstrate that ribosomal RNAs as well as polyA-RNAs move freely in a non-directional manner with a diffusion coefficient of 0.03–0.1 µm^2 s-1 within the nucleus |
| Entered by | Uri M |
| ID | 104211 |