| Value |
2.9
mutation/(haploid genome×generation)
|
| Organism |
Nematode Caenorhabditis elegans |
| Reference |
Lynch M, et al. A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc Natl Acad Sci U S A. 2008 Jul 8 105(27):9272-7. p.9276 right column 2nd paragraphPubMed ID18583475
|
| Primary Source |
Baer CF. et al. , (2006) Cumulative effects of spontaneous mutations for fitness in Caenorhabditis: Role of genotype, environment and stress. Genetics 174:1387–1395.PubMed ID16888328
|
| Comments |
"A comparable analysis yields a similar conclusion for C. elegans. This species incurs an estimated 2.9 mutations per haploid genome per generation (2.1 base substitutions and small insertion/deletions, 0.8 homopolymeric run changes, and 0.01 microsatellite mutations), whereas the genome-wide deleterious mutation rate has been consistently estimated as ˜0.015 (refs 45, 46), implying that ˜0.5% of mutations in this species have discernible effects on fitness." See BNID 100290 |
| Entered by |
Uri M |
| ID |
103520 |