Haploid genomic mutation rate

Value 0.99 mutation/genome/generation
Organism Fruit fly Drosophila melanogaster
Reference Lynch M, Sung W, Morris K, Coffey N, Landry CR, Dopman EB, Dickinson WJ, Okamoto K, Kulkarni S, Hartl DL, Thomas WK. A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc Natl Acad Sci U S A. 2008 Jul 8 105(27):9272-7.PubMed ID18583475
Primary Source Haag-Liautard C, Dorris M, Maside X, Macaskill S, Halligan DL, Houle D, Charlesworth B, Keightley PD. (2007) Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila. Nature 445:82–85.PubMed ID17203060
Comments 5 percent of these mutations appear to affect fitness
Entered by Uri M
ID 103522