Force required to package DNA to innermost radius in capsid
| Value | 12 pN |
|---|---|
| Organism | Bacteriophage Lambda |
| Reference | Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA. Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. Biopolymers. 2007 Feb 585(2):115-30.PubMed ID17103419 |
| Method | Model of tightly packed viral DNA. This model predicts the innermost radius of lambda DNA as 3 nm |
| Comments | pN=picoNewton=10^-12Newton. The force required to pack DNA into capsid increases as DNA is further packed along 'inversed spool' |
| Entered by | Uri M |
| ID | 103125 |