Intracapsid pressure resulting from DNA packaging

Value 60 Atm
Organism Bacteriophage phi 29
Reference Smith DE, Tans SJ, Smith SB, Grimes S, Anderson DL, Bustamante C. The bacteriophage straight phi29 portal motor can package DNA against a large internal force.Nature. 2001 Oct 18413(6857):748-52.PubMed ID11607035
Comments As the prohead is filled beyond 50% of its capacity, an internal force due to DNA confinement builds, reaching intracapsid pressures of 60 atm. This pressure may be used during infection to inject the DNA into a host cell
Entered by Uri M
ID 103129