Rate of RNAP transcription

Value 1400 bp/min
Organism Fruit fly Drosophila melanogaster
Reference Progression of the cell cycle through mitosis leads to abortion of nascent transcripts, Shermoen and O'Farrell, 1991, Oct 18 67(2):303-10 abstract & p.304 right column bottom paragraphPubMed ID1680567
Method Abstract: "Nascent transcripts of the Drosophila Ubx gene were detected by in situ hybridization. Following onset of expression, the progress of RNA polymerase (1.4 kb/min) across the gene was visualized as the successive appearance of hybridization signals from different positions within the transcription unit."
Comments P.304 right column bottom paragraph: "Based on the physical distance between these probes and the time of appearance of the signals, [investigators] estimate a transcriptional elongation rate of about 1.4 kb/min and 55min to traverse the entire Ubx transcription unit." 23.3 bp/sec
Entered by Uri M
ID 103003