Number of alpha and beta globin transcripts produced in developing erythrocyte
| Range | 10000-20000 copies/cell |
|---|---|
| Organism | Mouse Mus musculus |
| Reference | Voon HP, Vadolas J. Controlling {alpha}-globin: a review of {alpha}-globin expression and its Impact on {beta}-thalassemia. Haematologica. 2008 Sep 2. [Epub ahead of print] link PubMed ID18768527 |
| Primary Source | Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. EMBO J. 2004 Jul 2123(14):2847.PubMed ID15215894 |
| Comments | These mature, stabilized transcripts are utilized repeatedly to generate an estimated 280 million molecules of complete hemoglobin molecules per cell. |
| Entered by | Uri M |
| ID | 102291 |