Number of genes

Value 5268 genes
Organism Plasmodium falciparum
Reference Gardner et al. Genome sequence of the human malaria parasite Plasmodium falciparum. 2002. Nature. 419(6906):498-511. p.499 left column top paragraph & table 1PubMed ID12368864
Method "A whole chromosome shotgun sequencing strategy was used to determine the genome sequence of P. falciparum clone 3D7." "The structures of protein-encoding genes were predicted using several gene-finding programs and manually curated."
Comments "The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million African children annually." "The P. falciparum 3D7 nuclear genome is composed of 22.8 megabases (Mb) distributed among 14 chromosomes ranging in size from approximately 0.643 to 3.29 Mb (Fig. 1, and Supplementary Figs A–N)." "Approximately 5,300 protein-encoding genes were identified, about the same as in S. pombe (Table 1, and Supplementary Table A). This suggests an average gene density in P. falciparum of 1 gene per 4,338 base pairs (bp), slightly higher than was found previously with chromosomes 2 and 3 (1 per 4,500 bp and 1 per 4,800 bp, respectively)." Note to value of 5,268, beneath table 1:"*70% of these genes matched expressed sequence tags or encoded proteins detected by proteomics analyses [refs 14,15]" Since there are 5268 genes, there are 5268 proteins predicted. On 14 chromosomes.
Entered by Phil Mongiovi
ID 102196