Average speed of H69 small cell lung cancer cell

Range 0.26 μm/min
Organism Human Homo sapiens
Reference Maulik G et al., Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer. J Cell Mol Med. 2002 Oct-Dec6(4):539-53. DOI: 10.1111/j.1582-4934.2002.tb00453.x p.544 right column 2nd paragraphPubMed ID12611639
Method P.544 right column 2nd paragraph: "Time-lapse video microscopy analysis of cellular morphology, motility and clustering of serum starved H69 cells without or with HGF (100 ng/ml) was performed for 4 hours in the presence or absence of LY294002 (50 µM)."
Comments P.544 right column 2nd paragraph: "[Researchers] investigated the effect of HGF on the resultant speed of cellular motility/migration for H69 treated with or without HGF (100 ng/ml) in the presence or absence of LY294002. It was observed that in the absence of LY294002, the speed of the clusters was higher (mean = 0.26 µm/min) (with or without HGF) as compared to the cells in the presence of LY 294002 (mean = 0.091 µm/min) (figure 4B). It was also observed that in the absence of LY 294002, the average speed for the cells treated with HGF (speed = 0.35 µm/min) was much higher than that without HGF (speed = 0.17 µm/min)." LY294002=Phosphatidylinositol-3 kinase inhibitor. HGF=hepatocyte growth factor
Entered by Uri M
ID 106815