Number of VGLUT1 in typical synaptic vesicle

Value 9 copies/vesicle
Organism Rat Rattus norvegicus
Reference Takamori S et al., Molecular anatomy of a trafficking organelle. Cell. 2006 Nov 17 127(4):831-46. DOI: 10.1016/j.cell.2006.10.030 p.839 table 2PubMed ID17110340
Method P.836 right column bottom paragraph: "To construct a molecular model of a prototypic SV, [investigators] first calculated the average copy number per vesicle of the proteins quantified above (see Figure 1) based on the known molecular mass, Avogadro's number, and the average protein content per vesicle (Table 2, see also Table S2)."
Comments P.839 note C beneath table 2: "Corrected for the fraction of cells found to be positive by immunogold electron microscopy for the respective transporter."
Entered by Uri M
ID 102770