Area and thickness cardiac patch should have in order to have clinical utility

Range area 10-50cm^2: thickness several millimeters
Organism Human Homo sapiens
Reference Vunjak-Novakovic G et al., Challenges in cardiac tissue engineering. Tissue Eng Part B Rev. 2010 Apr16(2):169-87. doi: 10.1089/ten.TEB.2009.0352. p.174 right column bottom paragraphPubMed ID19698068
Comments P.174 right column bottom paragraph: "For clinical utility, an engineered cardiac patch should have an area of 10–50 cm^2 and a thickness of several millimeters. Several tissue engineering technologies are able to create a cardiac patch of a large enough surface area, but engineering viable millimeters thick cardiac constructs and their integration to the vascular supply of the host remain major challenges."
Entered by Uri M
ID 113201