Traditional pair-wise alignment of amino acids defining genes as belonging to the same gene family

Value >=50 %
Organism Generic
Reference Thornton JW, DeSalle R. Gene family evolution and homology: genomics meets phylogenetics. Annu Rev Genomics Hum Genet. 2000 1 :41-73. p.41PubMed ID11701624
Primary Source Graur D, Li WH. 1999. Fundamentals of Molecular Evolution. Sunderland, MA: Sinauer. 2nd ed.481 pp.
Comments Traditionally, a gene family has been defined as a group of genes all of whose members have >50% pairwise amino acid similarity.
Entered by Uri M
ID 105846