Number of base pairs between Lac operators creating DNA loop with minimum looping energy

Value 70.5 bp
Organism Bacteria Escherichia coli
Reference Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA. Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. Biopolymers. 2007 Feb 585(2):115-30.PubMed ID17103419
Primary Source Müller J, Oehler S, Müller-Hill B. Repression of lac promoter as a function of distance, phase and quality of an auxiliary lac operator. J Mol Biol. 1996 Mar 22257(1):21-9PubMed ID8632456
Method In a detailed approach, the researchers have systematically varied the distance between two lac operators from 57.5 bp to about 1500 bp on the bacterial chromosome.
Entered by Uri M
ID 103165