| Range |
~400 molecules/release/varicosity
|
| Organism |
Unspecified |
| Reference |
Krnjević, K. "Chemical nature of synaptic transmission in vertebrates." Physiological Reviews pp.418-540 :(1974) 54.2 p.468 3rd paragraph |
| Primary Source |
[527] Haggendal, J. On release of transmitter from adrenergic nerve terminals at nerve activity. Acta Physiol. Scand. Suppl. 330: 29, 1969. |
| Comments |
P.468 3rd paragraph: "If one assumes that every nerve impulse liberates NE [Norepinephrine] from all the terminal varicosities of a given fiber, the mean release per varicosity (about 400 molecules) is only about 2.5 % of the estimated content per vesicle (primary source). Can vesicles release just a small fraction of their NE content? Perhaps the vesicles from which the release takes place contain untypically small amounts of NE." |
| Entered by |
Uri M |
| ID |
115057 |