Global half-lives of mRNA in laboratory-grown E. coli cells

Range ~5 (1 - 8) min
Organism Bacteria Escherichia coli
Reference Moran MA et al., Sizing up metatranscriptomics. ISME J. 2013 Feb7(2):237-43. doi: 10.1038/ismej.2012.94. p.238 left columnPubMed ID22931831
Primary Source Ingraham JL, Maaløe O, Neidhardt FC. (1983). The Growth of the Bacterial Cell. Sinauer Associates: Sunderland, MA. & Bernstein JA, Khodursky AB, Lin P-H, Lin-Chao S, Cohen SN. (2002). Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci USA 99: 9697–9702. & Selinger DW, Saxena RM, Cheung KJ, Church GM, Rosenow C. (2003). Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation. Genome Res 13: 216–223. & Taniguchi Y, Choi PJ, Li G-W, Chen H, Babu M, Hearn J et al. (2010). Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. Science 329: 533–538.PubMed ID12119387, 12566399, 20671182
Comments P.238 left column:"Various measures of global half-lives of mRNA in laboratory-grown E. coli cells converge at about 5 min (range: ~1–8 min primary sources)."
Entered by Uri M
ID 111927