| Range |
31% C. elegans: 21% E. coli: 20% D. melanogaster %
|
| Organism |
Eukaryotes |
| Reference |
Almén MS, Nordström KJ, Fredriksson R, Schiöth HB. Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin. BMC Biol. 2009 Aug 13 7: 50. p.2/14 left column top paragraphPubMed ID19678920
|
| Primary Source |
Krogh A, Larsson B, von Heijne G, Sonnhammer EL. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol. 2001 Jan 19 305(3):567-80.PubMed ID11152613
|
| Method |
The membrane topology prediction method
TMHMM (TransMembrane prediction using Hidden Markov Models) was applied on a number of proteomes from
different species to estimate the membrane protein content |
| Comments |
Primary source abstract:"Based on these predictions, [investigators] estimate that 20-30 % of all genes in most genomes encode membrane proteins, which is in agreement with previous estimates." |
| Entered by |
Uri M |
| ID |
106431 |