Number of spurious transcription factor binding sites per genome

Range 10^2 to 10^4 Spurious sites per transcription factor
Organism Budding yeast Saccharomyces cerevisiae
Reference Wunderlich Z, Mirny LA. Different gene regulation strategies revealed by analysis of binding motifs. Trends Genet. 2009 Oct25(10):434-40. p.437 left column 2nd paragraphPubMed ID19815308
Method Using information theory and simulations, researchers estimate the lower bound of the number of such spurious sites or hits as h=2^(Imin-I), with an average spacing s=2^I between them
Comments Assuming 0 to 80% chromatinization. See BNID 106212
Entered by Uri M
ID 106213