Partial molecular volumes of carbohydrates

Range monosaccharide 184.9±1.4: disaccharide 346.2±5.4: trisaccharide 507.7±4.2 10^-3×nm^3
Organism Generic
Reference Perkins SJ. Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences. Eur J Biochem. 1986 May 15 157(1):169-80. p.170 right column 2nd paragraphPubMed ID3709531
Primary Source Fereidoon Shahidi, Patrick G. Farrell & John T. Edward, Partial molar volumes of organic compounds in water. III. Carbohydrates, Journal of Solution Chemistry, December 1976, Volume 5, Issue 12, pp 807-816
Method Densitometry data
Comments P.170 right column 2nd paragraph:"Densitometry data on saccharides are reported in [primary source]. From these data, the average monosaccharide, disaccharide and trisaccharide partial molecular volumes are calculated as 184.9(±1.4)x10^-3nm^3 (five values), 346.2(±5.4)x10^-3nm^3 (six values) 507.7(±4.2)x10^-3nm^3 (four values). The differences between these volumes show that the volume of polysaccharide condensation is 23.5 - 23.6x10^-3nm^3. This difference was used to correct the densitometric volumes of the free Glc, Gal and Man carbohydrates to their residue form (Table 3). Since these three volumes are on average 5.4x10^-3nm^3 smaller than those derived from monosaccharide crystal structures (Table 3), densitometric volumes for GlcNAc, GalNAc, Fuc and NeuNAc residues were estimated using this difference to correct the crystal volumes of these residues."
Entered by Uri M
ID 112197