| Range |
~80 rows
|
| Organism |
Fruit fly Drosophila melanogaster |
| Reference |
Petkova MD, Little SC, Liu F, Gregor T. Maternal origins of developmental reproducibility. Curr Biol. 2014 Jun 2 24(11):1283-8. doi: 10.1016/j.cub.2014.04.028. p.1283 left column bottom paragraphPubMed ID24856210
|
| Primary Source |
Gergen, J.P., Coulter, D., and Wieschaus, E.F. (1986). Segmental pattern and blastoderm cell identities. In Gametogenesis and the Early Embryo, J.G. Gall, ed. (New York: Alan R. Liss, Inc.), pp. 195–220. |
| Comments |
"Cells along the anterior-posterior (AP) axis of the developing
Drosophila embryo determine their location by interpreting
concentrations of morphogen molecules that correlate with
AP position. One process leading to these molecular patterns
(reviewed in [8]) originates in the female during oogenesis
when maternal mRNA of the anterior determinant bicoid
(bcd) is localized at the anterior pole of the egg. Upon egg activation,
these mRNA molecules serve as sources for a protein
gradient, which triggers a network of interacting genes that
generate a cascade of increasingly diversified molecular
spatial patterns, eventually specifying unique fates for each
of the ~80 rows of cells along the AP axis [primary source]." |
| Entered by |
Uri M |
| ID |
111201 |