Molecular mass of RNA polymerase II

Range 500 - 600 kDa
Organism Eukaryotes
Reference Sawadogo M, Sentenac A. RNA polymerase B (II) and general transcription factors. Annu Rev Biochem. 1990 59 :711-54. p.717 2nd paragraphPubMed ID2197989
Comments "Of the three forms of RNA polymerases, the B enzyme has been the most widely studied at the structural level. This multisubunit enzyme, of molecular mass 500,000-600,000, is composed of two large polypeptides (Mr>140,000) and a collection of smaller components . This polypeptide composition seems highly conserved in lower eukaryotes, plants, insects, and vertebrates (refs 2-4)."
Entered by Uri M
ID 110130