Combined molecular mass of six subunits of origin recognition complex

Value 414 kDa
Organism Budding yeast Saccharomyces cerevisiae
Reference Lee DG, Bell SP. Architecture of the yeast origin recognition complex bound to origins of DNA replication. Mol Cell Biol. 1997 Dec17(12):7159-68.PubMed ID9372948
Comments Six ORC subunits comprising orc are referred to as Orc1p through Orc6p (in order of decreasing mass), and all six proteins are essential for the viability of yeast cells. DNA binding domain of ORC requires the coordinate action of five of the six ORC subunits.
Entered by Uri M
ID 102576