Tabulation of ligand-receptor unbinding forces and the corresponding thermodynamic values

Range Table - link
Organism Generic
Reference VT. Moy, EL. Florin, HE. Gaub, Intermolecular forces and energies between ligands and receptors. Science. 1994 Oct 14 266(5183):257-9. p.257 fig.1APubMed ID7939660
Primary Source See refs beneath table
Method AFM (atomic force microscopy, scan mode)
Comments p.257 middle column 2nd paragraph:"The Unbinding force of five different avidin-biotin pairs varied from 85±10pN for avidin-iminobiotin to 257±25 pN for streptavidin-biotin (Fig. 1A).An examination of the corresponding thermodynamic energies revealed no obvious correlation between unbinding forces and changes in free energy ΔG (Fig. 1B). However, a linear relation between unbinding forces and enthalpy changes ΔH is evident (Fig. 1C)."
Entered by JoeG
ID 111926