Doubling time in a new-born (human) baby

Value 19.7 hours
Organism Bacteria Klebsiella oxytoca
Reference Gibson B, Wilson DJ, Feil E, Eyre-Walker A. The distribution of bacterial doubling times in the wild. Proc Biol Sci. 2018 Jun 13 285(1880). pii: 20180789. doi: 10.1098/rspb.2018.0789 p.6 right column top paragraphPubMed ID29899074
Primary Source [53] Brown CT, Olm MR, Thomas BC, Banfield JF. 2016 Measurement of bacterial replication rates in microbial communities. Nat. Biotechnol. 34, 1256–1263 DOI: 10.1038/nbt.3704PubMed ID27819664
Method Primary source abstract: "[Investigators] developed an algorithm, iRep, that uses draft-quality genome sequences and single time-point metagenome sequencing to infer microbial population replication rates. The algorithm calculates an index of replication (iRep) based on the sequencing coverage trend that results from bi-directional genome replication from a single origin of replication."
Comments P.6 right column top paragraph: "By contrast, Brown et al. [primary source] estimate the growth rate of Klebsiella oxytoca to be 19.7 h in a new-born baby using faecal counts and find that this population has an iRep value of approximately 1.77. This value is greater than the vast majority of bacteria in the human microbiome and bacteria in the Candidate Phyla Radiation, suggesting that most bacteria in these two communities replicate very slowly."
Entered by Uri M
ID 115548