Maximal firing frequency of neuron in basolateral amygdala at postnatal day 7 (P(7)) and 14 (P(14))

Range P7 15.9±3.3Hz: P14 33.9±7.3Hz Hz
Organism Rat Rattus norvegicus
Reference Ehrlich DE, Ryan SJ, Rainnie DG. Postnatal development of electrophysiological properties of principal neurons in the rat basolateral amygdala. J Physiol. 2012 Oct 1 590(19):4819-38. doi: 10.1113/jphysiol.2012.237453 p.4828 right column top paragraphPubMed ID22848043
Method Abstract: "[Investigators] addressed this critical knowledge gap [how BLA [basolateral amygdala] development contributes to emotional development or the aetiology of psychiatric disorders] for the first time using whole-cell patch clamp recording in rat BLA principal neurons to measure electrophysiological properties at postnatal day (P)7, P10, P14, P21, P28 and after P35."
Comments P.4828 right column top paragraph: "Interestingly, although the maximal firing frequency (mean ± SD) significantly increased (P < 0.001, one‐way ANOVA with Tukey's post hoc test, F3,23= 25.96) from P7 (15.9 ± 3.3 Hz) to P14 (33.9 ± 7.3 Hz), the transitions (P > 0.05) from P14 to P21 (34.7 ± 3.7 Hz) and from P21 to P28 (36.5 ± 4.2 Hz) were not significant."
Entered by Uri M
ID 115073