Composition of subunits of ribosome (see comments section for number of nts & aa)

Range large 60S subunit ~61% RNA 39% protein: small 40S subunit 54% RNA 46% protein %
Organism Budding yeast Saccharomyces cerevisiae
Reference Verschoor A, Warner JR, Srivastava S, Grassucci RA, Frank J. Three-dimensional structure of the yeast ribosome. Nucleic Acids Res. 1998 Jan 15 26(2):655-61. p.655 left column bottom paragraphPubMed ID9421530
Comments "The yeast ribosome is composed of two subunits. The 60S subunit contains three RNA molecules: 25S RNA of 3392 nt, hydrogen bonded to the 5.8S RNA of 158 nt and associated with the 5S RNA of 121 nt. There are 42 proteins in the large subunit, plus two copies each of two acidic exchangeable proteins. Altogether there are 3671 nt and 7235 amino acids in the 60S subunit, giving it a ratio of ~61% RNA to 39% protein. The 40S subunit has a single RNA of 1798 nt and 32 proteins with a total of 4749 amino acids, giving it a ratio of 54% RNA to 46% protein."
Entered by Uri M
ID 111541