| Value |
1.64e-3
cm/sec
Range: ±0.00015 Table - link cm/sec
|
| Organism |
Human Homo sapiens |
| Reference |
Forster RE, Gros G, Lin L, Ono Y, Wunder M. The effect of 4,4'-diisothiocyanato-stilbene-2,2'-disulfonate on CO2 permeability of the red blood cell membrane. Proc Natl Acad Sci U S A. 1998 Dec 22 95(26):15815-20. p.15818 table 1PubMed ID9861053
|
| Method |
"The reactions take place in an
airtight 3-ml glass water-jacketed and stirred chamber connected
to the ion source of a mass spectrometer through a thin
0.012-mm-thick Teflon membrane supported by a sintered
glass disc, through which gases are dissolved in the solution
diffuse. The chamber has a glass pH electrode and a removable
stopper for the addition of reactants." |
| Comments |
"DIDS (100µM) did not alter the calculated CA [carbonic anhydrase]
activity in the intact red cells, but did lower Pm,HCO3-
to about
half. The interesting finding is that membrane CO2 permeability,
from a value of 1cm/sec or higher in the control
experiments, was lowered by the drug to a value of 0.1cm/sec." |
| Entered by |
Uri M |
| ID |
110616 |