Assumed ERK concentration in human mammary epithelial cells

Value 1.2 μM
Organism Human Homo sapiens
Reference Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS. Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor. Mol Syst Biol. 2009 5: 332. doi: 10.1038/msb.2009.90. p.6 right column 2nd paragraphPubMed ID19953086
Comments "...[Researchers] assumed that the total ERK concentration in wild-type HMEC is 1.2µM (expressed in terms of the cytoplasmic volume), a number that is based on estimates in other cell types (Huang and Ferrell, 1996 Brightman and Fell, 2000 Schoeberl et al, 2002 Fujioka et al, 2006).
Entered by Uri M
ID 108754