Volume of U2OS (human osteosarcoma U2OS cell line) cell

Range ~4,000 μm^3
Organism Human Homo sapiens
Reference Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. The quantitative proteome of a human cell line. Mol Syst Biol. 2011 Nov 87:549. doi: 10.1038/msb.2011.82. p.5 left column 2nd paragraphPubMed ID22068332
Comments "In the present study, [researchers] demonstrate that the protein copy numbers of a human cell span at least seven orders of magnitude. This range is similar to that determined in mouse cells (Schwanhausser et al, 2011). This finding is furthermore in good agreement with the volume of the relevant cell types, namely ~0.2µm^3 in L. interrogans (Beck et al, 2009), and about ~30µm^3 in S. cerevisiae and ~4000µm^3 in U2OS, (assuming spherical shape and 4 and 20µm diameter for yeast and U2OS, respectively)."
Entered by Uri M
ID 108088