Maximum migration speed of mouse 3T3 cells

Range ≈40 μm/hour
Organism Mammalian tissue culture cell
Reference Kim DH, Han K, Gupta K, Kwon KW, Suh KY, Levchenko A. Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients. Biomaterials. 2009 Oct30(29):5433-44. p.5437 left column bottom paragraphPubMed ID19595452
Method Ultraviolet (UV)-assisted capillary force lithography (CFL)
Comments "Although both cell alignment and elongation was directly proportional to the density of the topography, [researchers] observed that the cell speed depended biphasically on the topographic density, with the fastest migration (˜40 µm/h) occurring at an intermediate ridge pattern density (positioned between 200 µm and 300 µm the range of groove widths: 5.6 –6.9 µm) (Fig. 3d)."
Entered by Uri M
ID 108382