| Value |
15
%
|
| Organism |
Eukaryotes |
| Reference |
Benjamin Lewin, Genes VIII 2004, p.359 4th paragraph |
| Method |
As eukaryotic replicons are 40 to 100 kb long and the rate of replication is ~2,000bp/min it is evident that a mammalian genome could be replicated in ~1hour if all replicons functioned simultaneously. But S phase actually lasts for >6hours in a typical somatic cell, which implies that no more than 15% of the replicons are likely to be active at any given moment. |
| Comments |
There are some exceptional cases, such as the early embryonic divisions of the Drosophila embryos, where the duration of S phase is compressed by the simultaneous functioning of a large number of replicons. |
| Entered by |
Uri M |
| ID |
106929 |