Lifespan of an infected cell

Range 12-40 hours
Organism Influenza
Reference Zhirnov OP, Konakova TE, Wolff T, Klenk HD. NS1 protein of influenza A virus down-regulates apoptosis. J Virol. 2002 Feb76(4):1617-25. p.1620 left columnPubMed ID11799156
Comments MDCK and Vero cells in vitro. Whereas delNS1 virus caused prominent apoptosis in MDCK cells already at 12 to 20 h after infection (hpi), intensive cell rounding and detachment, marked DNA laddering, and NP cleavage developed at 35 to 40 hpi in Vero cells.
Entered by Andreas Handel
ID 101610