Diffusion coefficient small GFP in cytoplasm

Range ~30 μm^2/sec
Organism Amoeba Dictyostelium discoideum
Reference D.N. Robinson, Y.-S. Kee, T. Luo and A. Surcel, Understanding How Dividing Cells Change Shape. In: Edward H. Egelman, editor: Comprehensive Biophysics, Vol 7, Cell Biophysics, Denis Wirtz. Oxford: Academic Press, 2012. pp. 48-72. p.66 left column 2nd paragraph
Comments "Poroelasticity largely implicates a biphasic cellular medium in which an interconnected elastic cytoskeleton is filled with a viscous cytoplasm. Indeed, from the diffusion coefficient (~30µm^2/sec) measured for the small GFP protein, the cytoplasmic viscosity experienced by a particle this size is only about threefold more than for water (10^-6 nN?s/µm^2)(refs 169,170)."
Entered by Uri M
ID 109572