ATP molecules to be hydrolyzed to initiate the action potential and propagate it
| Value | 3.84e+8 ATP/action potential |
|---|---|
| Organism | Unspecified |
| Reference | Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001 Oct21(10):1133-45. p.1136 right column top paragraphPubMed ID11598490 |
| Comments | "A realistic estimate of the Na+ entry needed is obtained by quadrupling this to take account of simultaneous activation of Na+ and K+ channels (Hodgkin, 1975), resulting in 11.5×10^8Na+ which have to be pumped out again, requiring 3.84×10^8ATP molecules to be hydrolyzed (Figs. 1B, 2, and 3)." |
| Entered by | Uri M |
| ID | 108652 |