Circulating half life of neutrophils (the most abundant subpopulation of leukocytes)

Range 6 - 8 hours
Organism Unspecified
Reference Birbrair A, Frenette PS. Niche heterogeneity in the bone marrow. Ann N Y Acad Sci. 2016 Apr1370(1):82-96. doi: 10.1111/nyas.13016 p.90 left column 3rd paragraphPubMed ID27015419
Primary Source [209] Summers C et al., Neutrophil kinetics in health and disease. Trends Immunol. 2010 Aug31(8):318-24. doi: 10.1016/ ID20620114
Comments P.90 left column 3rd paragraph: "Neutrophils have a short circulating half‐life (6–8 h), after which they quickly migrate to tissues where they perform their functions (primary source)." Primary source abstract: "Neutrophils play a key role in the elimination of pathogens. They are remarkably short-lived with a circulating half life of 6-8h and hence are produced at a rate of 5×10^(10)-10×10^(10) cells/day."
Entered by Uri M
ID 117065