Ratio of mitochondrial matrix water to cytosol water in myocyte

Range ≈1:4 matrix water:cytosol water
Organism Rat Rattus norvegicus
Reference Anastacio MM et al., Relationship between mitochondrial matrix volume and cellular volume in response to stress and the role of ATP-sensitive potassium channel. Circulation. 2013 Sep 10 128(11 Suppl 1):S130-5. doi: 10.1161/CIRCULATIONAHA.112.000128 p.S131 left column 3rd paragraphPubMed ID24030396
Primary Source [14] Bakeeva LE, Chentsov YuS, Skulachev VP. Mitochondrial framework (reticulum mitochondriale) in rat diaphragm muscle. Biochim Biophys Acta. 1978 Mar 13 501(3):349-69PubMed ID629958
Method Primary source [14] abstract: "Reconstitution of rat diaphragm mitochondria has been carried out with the use of the serial section technique."
Comments P.S131 left column 3rd paragraph: "The ratio of matrix water to cytosol water is ≈1:4, and the influx of water into the mitochondria could cause depletion in cytosolic inorganic phosphates, leading to an increased rate of reactive oxygen species production, thereby benefiting the myocyte [primary source]."
Entered by Uri M
ID 116937