Number of type III Secretion effector protein SopE expressed by sipA expressing bacteria

Value 1000 molecules of SopE/cell Range: ±500 molecules of SopE/cell
Organism Bacteria Salmonella typhimurium
Reference Schlumberger MC et al., Real-time imaging of type III secretion: Salmonella SipA injection into host cells. Proc Natl Acad Sci U S A. 2005 Aug 30 102(35):12548-53 DOI: 10.1073/pnas.0503407102 p.12552 right column bottom paragraphPubMed ID16107539
Primary Source [25] Darwin KH, Miller VL. Type III secretion chaperone-dependent regulation: activation of virulence genes by SicA and InvF in Salmonella typhimurium. EMBO J. 2001 Apr 17 20(8):1850-62 DOI: 10.1093/emboj/20.8.1850PubMed ID11296219
Method Abstract: "By using time-lapse microscopy, [investigators] have imaged delivery of the Salmonella type III effector protein SipA/SspA into animal cells in real time."
Comments P.12552 right column bottom paragraph: "As expected from earlier studies (primary source), all sipA expressing bacteria also expressed sopE (1,000 ± 500 molecules of SopE per cell) (Fig. 11, which is published as supporting information on the PNAS web site)."
Entered by Uri M
ID 115220