| Range |
≈90 µm^3
|
| Organism |
Human Homo sapiens |
| Reference |
Wagner BA, Venkataraman S, Buettner GR. The rate of oxygen utilization by cells. Free Radic Biol Med. 2011 Aug 1 51(3):700-12. doi: 10.1016/j.freeradbiomed.2011.05.024 p.707 right column bottom paragraphPubMed ID21664270
|
| Primary Source |
[58] Child JA, King J, Newman TH, Waterfield RL. A diffraction method for measuring the average volumes and shapes of red blood cells. Br J Haematol. 1967 May13(3):364-75.PubMed ID6025246
|
| Method |
Primary source p.364 top paragraph: "Two suspensions of the cells are set up in isotonic salt solution, one containing 1 per cent formalin, and the other a trace of detergent. In the first the cells are fixed in their natural discoidal form, in the second the cells are converted into spheres, the metamorphosis from disc to sphere occurring without change of volume. The suspensions are introduced into shallow glass chambers and the cells allowed to settle in a unicellular layer. Measurement of the spherical cells gives the mean diameter of the spheres, and hence MCV (mean cell volume). Measurement of the discoidal cells gives MCD (mean cell diameter), which combined with MCV gives D/T (diameter-thickness ratio). Owing to the shrinkage with formalin, the values of MCD and D/T are necessarily relative." |
| Comments |
P.707 right column bottom paragraph: "The volume of cells varies considerably, from ≈ 0.5 fl (5×10^−4 pl) for a bacterial cell [refs 55, 56] to ≈ 40 fl (4×10^−2 pl) for yeast [ref 57], ≈ 90 fl (9×10^−2 pl) for human erythrocytes [primary source], 0.30 pl for human neutrophils [ref 59 BNID 115153], 1.76 pl for MCF-7 cells [ref 60 BNID 115154], and 6.2 pl for rat hepatocytes [ref 53 BNID 115150]." |
| Entered by |
Uri M |
| ID |
115152 |