Length of average fragment that is generated by proteasomes
| Value | 7 residues (amino acids) |
|---|---|
| Organism | Rabbit |
| Reference | Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol. 2003 Dec3(12):952-61. DOI: 10.1038/nri1250 p.959 left column 2nd paragraphPubMed ID14647477 |
| Primary Source | [15] Cascio, P., Hilton, C., Kisselev, A. F., Rock, K. L. & Goldberg, A. L. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J. 20, 2357–2366 (2001) DOI: 10.1093/emboj/20.10.2357PubMed ID11350924 |
| Comments | P.959 left column 2nd paragraph: "If the average fragment that is generated by proteasomes is ~7 residues long [primary source], proteasomes would generate ~1.2×10^8 peptides per minute." |
| Entered by | Uri M |
| ID | 113793 |