| Range |
~2,600grams (of which 1,400 g are assumed to be actively participating in blood cell formation) grams
|
| Organism |
Human Homo sapiens |
| Reference |
Fliedner TM, Graessle D, Paulsen C, Reimers K. Structure and function of bone marrow hemopoiesis: mechanisms of response to ionizing radiation exposure. Cancer Biother Radiopharm. 2002 Aug17(4):405-26. doi:10.1089/108497802760363204. p.412 right column top paragraphPubMed ID12396705
|
| Comments |
P.412 left column bottom paragraph: "The data presented in the previous chapter of this presentation indicate the enormous cell turnover providing the organism with all essential blood cell elements that are necessary to supply the organism with oxygen (erythrocytes), with phagocytic elements that appear to clean continuously the mucous membrane by migrating through them into the inner surface of the organism (granulocytes) and to assure vascular integrity (platelets) (refs 1, 2, 3). It also was evident that the daily turnover of bone marrow produced cells is about 500 billion. Thus, the question is legitimate as to the detailed function of the organ system which is providing lifelong the essential blood cell elements to assure the integrity of the entire organism. The bone marrow is an organ of about 2,600 g of which 1,400 g are assumed to be actively participating in blood cell formation. It is
composed out of many sub-units that are distributed through the about 206 bones of the adult human organism acting as semi-autonomous organ units. These are part of the bone marrow system that acts as one organ due to the complex regulatory mechanisms that will be discussed in Chapter 4 of this review." |
| Entered by |
Uri M |
| ID |
113418 |