| Range |
5 - 7 days
|
| Organism |
Human Homo sapiens |
| Reference |
Fliedner TM, Graessle D, Paulsen C, Reimers K. Structure and function of bone marrow hemopoiesis: mechanisms of response to ionizing radiation exposure. Cancer Biother Radiopharm. 2002 Aug17(4):405-26. doi:10.1089/108497802760363204. p.409 left column 3rd paragraphPubMed ID12396705
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| Primary Source |
[30] Eaves JC and Eaves AC. Erythropoiesis. In: Golde WD and Takaku F, editors. Hematopoietic Stem Cells. New York: Marcel Dekker, Inc., 1985 [31] Killmann S-A, Cronkite EP, Fliedner TM and Bond VP. Mitotic indices of human bone marrow cells. III. Duration of some phases of erythrocytic and granulocytic proliferation computed from mitotic indices. Blood 1964 24 :267–280PubMed ID14214136
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| Comments |
P.409 left column 3rd paragraph: "The time to “rebuild” the granulocytic cell renewal system after hemopoietic stem cell transplantation is in the order of 10–12 days. It takes about 4 days for the granulocytes to mature after the last myelocyte division and to be released into the blood (ref 19). It takes about 6 days for cells from the myeloblast to the myelocyte stage (ref 19). Therefore, the replication of stem cells must be relatively rapid to produce enough cells to be triggered into the cellular proliferation and maturation process (ref 29). The transit time for erythropoietic cells from the earliest cell type (proerythroblast) to the release of red cells into the blood is about 5–7 days (primary sources), and the equivalent time to produce blood platelets is about 10 days in the human being (BNID 113415)." |
| Entered by |
Uri M |
| ID |
113416 |