| Range |
2 - 3 unitless
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Sauer U, Bailey JE. Estimation of P-to-O ratio in Bacillus subtilis and its influence on maximum riboflavin yield. Biotechnol Bioeng. 1999 Sep 20 64(6):750-4. DOI: 10.1002/(SICI)1097-0290(19990920)64:6<750::AID-BIT15>3.0.CO2-S link p.751 right column bottom paragraph PubMed ID10417225
|
| Primary Source |
Gottschalk G. 1986. Bacterial metabolism, 2nd edition. New York: Springer-Verlag. |
| Method |
Abstract: "Simultaneous growth and riboflavin overproduction were investigated using a previously developed stoichiometric model of Bacillus subtilis metabolism. A fit of model predictions to experimental data was used to obtain estimates of fundamental energetic parameters of B. subtilis." P.750 right column bottom paragraph: "A previously constructed stoichiometric model of B. subtilis
metabolism was used as published (Sauer et al., 1998). Briefly, mass balances on cellular metabolites provide a set of linear equations relating intracellular and external fluxes." |
| Comments |
P.751 right column bottom paragraph: "Electron Transport Chain Composition in B. subtilis: Compared with the Gram-negative bacteria, little is known about energy transduction in the respiratory metabolism of B. subtilis (Trumpower and Gennis, 1994). To see if there is any biological rationale for a lower P/O in B. subtilis than the maximum value of 2–3 assumed for Escherichia coli (primary source), [investigators] performed homology searches for respiratory chain components in the recently completed genome database of B. subtilis (Kunst et al., 1997) using the gapped Blast algorithm (Altschul et al., 1997)." |
| Entered by |
Uri M |
| ID |
113246 |