Size of initially multilamellar spherical vesicles and, after feeding, long thread-like small unilamellar fatty acid vesicles

Range spherical diameter ~3.1µm volume ~15.6µm^3: thread-like length ~81.1µm volume 15.3±0.6µm^3
Organism Generic
Reference Zhu TF, Szostak JW. Coupled growth and division of model protocell membranes. J Am Chem Soc. 2009 Apr 22 131(15):5705-13. doi: 10.1021/ja900919c. Supporting text page S4 bottom paragraphPubMed ID19323552
Method Abstract: "Here [investigators] describe a simple and efficient pathway for model protocell membrane growth and division."
Comments Supporting text page S4 bottom paragraph: "The estimation of the volume and surface area of a single vesicle before and after growth from high-resolution images (not shown in figures-available upon request) provided further evidence for volume conservation and surface area increase. Before growth, the vesicle diameter measured ~3.1 µm, which corresponds to a surface area of ~30.2 µm^2 and a volume of ~15.6 µm^3. After growth, the thread-like vesicle length measured ~81.1 µm and the width measured 0.49±0.02 µm (this scale is close to the resolution limit of optical microscopy, and results in larger measurement error), which corresponds to an estimated surface area of ~124.8±5.1 µm^2 (~4-fold increase from that before growth) and an estimated volume of ~15.3±0.6 µm^3."
Entered by Uri M
ID 113228