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P.327 left column: "Memory formation goes through successive stages of encoding. Hippocampally-based short term memory has long been known to require consolidation into long term memory in the cerebral cortex by a process that requires gene expression and new protein synthesis. In 2000, Nader et al. (2000, 2013) discovered a new later phase in memory storage called reconsolidation. Reconsolidation occurs after a long term memory is actively recalled and the old memory is reprocessed in such a way that it again requires new protein synthesis (Fig. 1). In addition to memory recall, there must be novel information or context for opening of the reconsolidation window (Agren, 2014 Ecker, 2015). Fig. 2. During this phase of reconsolidation, the memory trace becomes labile and subject to long term revision by psychological processes occurring within the reconsolidation window which lasts approximately 5 min to 1 h (and possibly up to 5 h) after the active memory recall." |