Fraction of outer leaflet of plasma membranes that is typically comprised of the phospholipids phosphatidylcholine and sphingomyelin

Range 50-90 %
Organism Eukaryotes
Reference Wargo MJ. Homeostasis and catabolism of choline and glycine betaine: lessons from Pseudomonas aeruginosa. Appl Environ Microbiol. 2013 Apr79(7):2112-20. doi: 10.1128/AEM.03565-12. p.2113 left column 2nd paragraphPubMed ID23354714
Primary Source [30] Zachowski A . 1993. Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochem. J. 294: 1–14.PubMed ID8363559
Comments P.2113 left column 2nd paragraph: "Soluble choline is measurable in some environments (∼8 μM in serum, 0 to 45 nM in seawater [BNID 112935]), but the most abundant source is thought to be the choline headgroup moiety on the eukaryotic phospholipids phosphatidylcholine and sphingomyelin, which together typically comprise 50 to 90% of the outer leaflet of eukaryotic plasma membranes (reviewed in reference 30)."
Entered by Uri M
ID 112936