Tilt of the bases in DNA

Range DNA 73˚: B-DNA 83˚ ˚
Organism Generic
Reference Record MT Jr et al., Double helical DNA: conformations, physical properties, and interactions with ligands. Annu Rev Biochem. 1981 50 :997-1024. p.999 3rd paragraphPubMed ID7023371
Primary Source [16] Mandelkern M, Dattagupta N, Crothers DM. Conversion of B DNA between solution and fiber conformations. Proc Natl Acad Sci U S A. 1981 Jul78(7):4294-8. [24] Hogan M, Dattagupta N, Crothers DM. Transient electric dichroism of rod-like DNA molecules. Proc Natl Acad Sci U S A. 1978 Jan75(1):195-9.PubMed ID6945584, 272634
Method P.999 3rd paragraph: "Electric dichroism measurements on DNA fragments."
Comments P.999 3rd paragraph: "Electric dichroism measurements on DNA fragments indicated that the tilt of the bases was not 83 deg as in the B-DNA structure but closer to 73 deg (primary sources), a value similar to that predicted by the conformational energy minimization technique of Levitt (ref 25). However a tilt of 83 deg was observed if measurements were done under conditions at which aggregation of DNA fragments occurs, which suggests that intermolecular interactions may affect structure (primary source 16)."
Entered by Uri M
ID 112616