Number of potential phosphorylation sites for any given kinase
| Range | ~700,000 potential sites/kinase |
|---|---|
| Organism | Eukaryotes |
| Reference | Ubersax JA, Ferrell JE Jr. Mechanisms of specificity in protein phosphorylation. Nat Rev Mol Cell Biol. 2007 Jul8(7):530-41. doi:10.1038/nrm2203 p.520 left column 2nd paragraphPubMed ID17585314 |
| Comments | P.520 left column 2nd paragraph: "If it is assumed that there are ~10,000 different proteins in a typical eukaryotic cell, with an average length of ~400 amino acids (~17% of which are Ser (8.5%), Thr (5.7%) or Tyr (3.0%) residues [ref 7, Echols et al, 2002 PMID 12034841]), then there are ~700,000 potential phosphorylation sites (P-sites) for any given kinase." Ref 7 studied eukaryotes |
| Entered by | Uri M |
| ID | 112582 |