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Hydrogen sulfide (H2S) concentration in healthy tissues and blood

Range	10-300 μM
Organism	Unspecified
Reference	Tangerman A. Measurement and biological significance of the volatile sulfur compounds hydrogen sulfide, methanethiol and dimethyl sulfide in various biological matrices. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 15 877(28):3366-77. doi: 10.1016/j.jchromb.2009.05.026. p.3367 right column top paragraphPubMed ID19505855
Primary Source	[21] S. Fiorucci, E. Distrutti, G. Cirino, J.L. Wallace, The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver. Gastroenterology. 2006 Jul131(1):259-71. [22] Szabó C. Hydrogen sulphide and its therapeutic potential. Nat Rev Drug Discov. 2007 Nov6(11):917-35. [23] Leslie M. Medicine. Nothing rotten about hydrogen sulfide's medical promise. Science. 2008 May 30 320(5880):1155-7. doi: 10.1126/science.320.5880.1155. [24] Morrison ML et al., Surviving blood loss using hydrogen sulfide. J Trauma. 2008 Jul65(1):183-8. doi: 10.1097/TA.0b013e3181507579. [25] Ubuka T. Assay methods and biological roles of labile sulfur in animal tissues. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Dec 5 781(1-2):227-49.PubMed ID16831608, 17948022, 18511669, 18580516, 12450661
Comments	P.3367 left column bottom paragraph:"In the past few years, H2S has also been postulated to be a biologically gaseous mediator with potential roles in several physiological processes and disease states [primary sources 21-24]. Most results were based on the finding of high concentrations of H2S (10–300 μM) in healthy tissues and blood [primary sources 21-25]." Primary source [24] studied rats, the other primary source abstracts didn't specify which organism they studied.
Entered by	Uri M
ID	112382