| Range |
arrestin-/- mice 0.8%/min: normal mice 1.0%/min %/min
|
| Organism |
Mouse Mus musculus |
| Reference |
Saari JC. Biochemistry of visual pigment regeneration: the Friedenwald lecture. Invest Ophthalmol Vis Sci. 2000 Feb41(2):337-48. p.343 left column 3rd paragraphPubMed ID10670460
|
| Method |
"...[researchers] examined the composition of retinoids during bleaching and regeneration in arrestin-/- mice. These animals were born and raised in the dark
and subjected to flash bleaching followed by a recovery period
in the dark. The distribution of visual cycle retinoids observed
before and after a flash is very similar to that seen with normal
mice (not shown)." |
| Comments |
"The recovery of 11-cis-retinal in the dark
was slower in arrestin-/- mice than in normal mice (0.6 and
1.1% per minute, respectively. Fig. 10). However, the rates of
rhodopsin regeneration were similar (0.8% per minute and 1%
per minute, respectively)." |
| Entered by |
Uri M |
| ID |
111399 |